Sajal Ghosh | Department of Physics

Profile

Sajal
Kumar
Ghosh
Assistant Professor
Department of Physics
School of Natural Sciences (SoNS)
A017D, Shiv Nadar University
Dadri Uttar Pradesh
India
+91-120-3819100
Extn: 
410
Profile Summary 

Sajal Kumar Ghosh did his Ph. D from Raman Research Institute, Bangalore, India. There after he joined as a post-doctoral scientist in the Institute for X-ray Physics, University of Goettingen, Germany. Then he moved to the University of California-San Diego (UCSD), California, USA to work as a post-doctoral scholar. Sajal has research experience in the field of soft matter physics including bio-physics. He has presented his research works in many international conferences in India, Japan, Germany, Italy, France, Spain, UK and USA. His present interests are in i) tuning viscoelastic properties of soft materials by altering the self-assembled aggregates, ii) developing simple model systems to facilitate physical and chemical studies of bio-systems, iii) developing devices which are useful for drug delivery, bio-sensing, non-destructive molecule counter etc. using nanotechnologies.

 
Educational Qualifications 
2008
PhD
Raman Research Institute, Bangalore, (Jawaharlal Nehru University, New Delhi)
2001
M.Sc
Department of Physics, University of Kalyani, West Bengal.
1999
B.Sc
Department of Physics, University of Kalyani, West Bengal.
Work Experience 
12/13Present
Assistant Professor
Department of Physics, School of Natural Sciences, Shiv Nadar University (SNU), Greater Noida, INDIA
I currently work here
11/10
11/13
Post-doctoral Scholar
Department of Physics, University of California- San Diego, USA.
04/08
10/10
Post-doctoral Scientist
Department of Physics, University of Goettingen, Germany
Teaching & Research Interests: 

TEACHING:             

PHY 252: Introduction to BioPhysics (Undergraduate Course)
PHY 569: Complex Fluids (Graduate Course)
PHY 108: Physics for life: A fundamental course (Undergraduate Course)
PHY 103: Fundamental of Physics – I (Undergraduate Course)                                                                                                                                                           PHY 101: Introduction to Physics I (Undergraduate Course for Engineering Major)
PHY 572: Soft Matter Physics (Graduate Course)
CCC 417: Physical Laws: from Nonliving to Living (Undergraduate Course)

RESEARCH  (http://physics.snu.edu.in/research/laboratories/soft-matter-physics...)   

We work in the field of experimental soft matter physics including biophysics. Soft materials used in cosmetic industries are investigated to explore their underlying structures and corresponding viscoelastic properties. These structures are altered by tuning the electrostatic interaction among the self-assembled aggregates in amphiphilic systems. In turn, the materials show interesting physical properties which are important for industrial applications. We also work in the field of membrane biophysics to develop model systems to investigate the interaction of macromolecules (e.g. protein, DNA etc.) with model cellular membranes. We are now embarking on to develop devices for bio-medical applications using nano-technology. Different x-ray scattering (x-ray diffraction, x-ray reflectivity, grazing incidence x-ray diffraction etc.) and microscopy techniques are used at in-house and international synchrotron facilities to study the structures and properties of such soft materials and bio-systems.

=> Research in the field of lyotropic liquid crystalline system                                                                                             http://physics.snu.edu.in/research/projects/tuning-self-assembled-a...

=> Research in the field of membrane biophysics                                                                                                                 http://physics.snu.edu.in/research/projects/investigating-toxicity-...

=> Research in the field of surface science                                                                                                                    http://physics.snu.edu.in/research/projects/nano-and-micro-structur...

RESEARCH STUDENTS   

Ph. D students

1. Saheli Mitra (Supervisor); DST-INSPIRE Fellow                                                                                                              http://physics.snu.edu.in/people/researchers/saheli-mitra

2. Priya Mandal (Supervisor)                                                                                                                                                     http://physics.snu.edu.in/people/researchers/priya-mandal

3. Yogesh Yadav (Co-supervisor with Dr. Samarendra P. Singh)                                                                                                      http://physics.snu.edu.in/people/researchers/yogesh-yadav

4. Ritika Gupta (Supervisor); UGC-DAE (Mumbai Centre) funded                                                                                     http://physics.snu.edu.in/people/researchers/ritika-gupta

5. Prashant Hitaishi (Supervisor): DST-SERB funded                                                                                                          https://physics.snu.edu.in/people/researchers/prashant-hitaishi

 'Opportunity for Undergraduate Research (OUR)' students 

Anamaya Shah and Uttam Italia

Group Alumni

1. Dr. Gourav Bhattacharya: Former PhD student. Presently a post-doc in Ulster University 

2. Nandita Singhal (UG research student)     

3. Aishwarya Sathya (UG research student)     

4. Shuverthi De Sarkar (UG research student)

Conferences (Select): 

1.Synchrotron X-rays and Neutron Scattering Studies of Anti-bacterial activities of Imidazolium-based Ionic Liquids, 63rd DAE-Solid State Physics Symposium, December 2018, Guru Jambheshwar University of Science and Technology, Hisar, India.

2. Effect of imidazolium-based ionic liquids on the structure and dynamics of cellular membrane: From model to mammalian membranes, November 2018, Department of Physics, University of Goettingen, Germany

3. Self-assembled structures of soft-materials by synchrotron x-ray scattering, December 2017, Discussion meeting on Synchrotron Science, Saha Institute of Nuclear Physics, Kolkata, India

2. Interaction of imidazolium-based ionic liquids with soft supported lipid membrane, 19th IUPAB and 11th EBSA Congress Edinburgh, July 2017, UK

3. Soft supported lipid bilayer to study cellular membrane, May 2015, Institute of Materials Structure Science, High Energy Accelerator Research Organization [Tokai Campus], Japan

4. Structural studies of lipid-protein interactions on cushioned bilayers, March, 2013, APS March Meeting 2013, Baltimore, MD, USA

5. Highly resolved structure of a floating lipid bilayer: Effect of Ca2+ ions and temperature, February 2013, 57th Annual Meeting of Biophysical Society, Philadelphia, USA

6. Interaction of Synaptic Vesicles with Model Lipid Membranes: A Structural Study, July 2010, International Soft Matter Conference 2010, Granada, Spain

7. Interaction of Synaptic Vesicles with Lipid Monolayers: A Structural Investigation by X-ray Reflectivity and GIXD, November 2009, Jülich Soft Matter Days 2009, Bonn, Germany

 

 

Awards(Selected): 

DST travel & experiment grants to perform synchortron experiments in Photon Factory (PF), KEK, Tsukuba, Japan: June 2015, November 2015, February 2017, April 2017, February 2018 & June 2018.

2017

DST travel grant to attend 19th International Union of Pure and Applied Biophysics (IUPAB) and 11th European Biophysical Societies' Association (EBSA) Congress in Edinburgh, Scotland.

2000

Scored in Joint Entrance Screening Test (JEST) in 2002 and research fellowship was awarded.

2000

Qualified Graduate Aptitude Test in Engineering (GATE) 

1997

Merit scholarship by University of Kalyani for ranking first in BSc.

Scholarly Activity

Journal Articles

24. S. Mitra, R. Karri, P. K Mylapalli, A. B. Dey, G. Bhattacharya, G. Roy, S. M. Kamil, S. Dhara, S. K. Sinha and S. K. Ghosh*, Re-entrant Direct Hexagonal Phases in a Lyotropic System of Surfactant Induced by an Ionic Liquid, Liquid Crystal (2019), Accepted for Publication (https://www.tandfonline.com/doi/full/10.1080/02678292.2019.1566507)

23. J.-Jin Song, R. Bhattacharya, Y. Yang, S. K. Ghosh, S. K. Sinha, H. Kim, J. Chang, H. Kim, T. P. Russell, T. Tang, G. Arya, H. Guo, S. Narayanan and Z. Jiang, One-Dimensional Anomalous Diffusion of Gold Nanoparticles in a Polymer Melt, Physical Review Letters (2019), 122, 107802 (https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.122.107802)

22. S. B. Srivastava, M. H. Modi, S. K. Ghosh and S. P. Singh, Investigation of the buried planar interfaces in multi-layered inverted organic solar cells using X-ray reflectivity and impedance spectroscopy, Journal of Physics-Condensed Matter (2019) 31(12):124003 (https://iopscience.iop.org/article/10.1088/1361-648X/aafe38/meta)

21. S. Mitra, D. Ray, G. Bhattacharya, R. Gupta, D. Sen,V. K. Aswal and S. K. Ghosh*, Probing the effect of a room temperature ionic liquid on phospholipid membranes in multilamellar vesicles, European Biophysics Journal (2019) 48(2):119-129 

20. G. Bhattacharya, R. P. Giri, A. Dubey, S. Mitra, R. Priyadarshni, A. Gupta, M. K. Mukhopadhyay and S. K. Ghosh*, Structural changes in cellular membranes induced by ionic liquids: From model to bacterial membranes, Chemistry & Physics of Lipids (2018), 215, 1-10 (https://doi.org/10.1016/j.chemphyslip.2018.06.001

19. G. Bhattacharya, S. Mitra, P. Mandal, S. Dutta, R. P. Giri and S. K. Ghosh*; Thermodynamics of interaction of ionic liquids with lipid monolayer; Biophysical Reviews (2018), 10, 709-719 (https://doi.org/10.1007/s12551-017-0390-3)

18. A. Barman, C. P. Saini, P. K. Sarkar, G. Bhattacharjee, G. Bhattacharya, S. Srivastava, B. Satpati, D. Kanjilal, S. K. Ghosh, S. Dhar, and A. Kanjilal; Resistive switching behavior in oxygen ion irradiated TiO2-x films; J.Phys. D: Appl Phys (2018),51, 065306 (https://doi.org/10.1088/1361-6463/aaa559) 

17. V. K. Sharma, S. K. Ghosh, P. Mandal, T. Yamada, K. Shibata, S. Mitra and R. Mukhopadhyay; Effects of ionic liquids on the nanoscopic dynamics and phase behaviour of a phosphatidylcholine membrane. Soft Matter (2017), 13, 8969. (http://pubs.rsc.org/-/content/articlehtml/2017/sm/c7sm01799e)   

16. G. Bhattacharya, R. P. Giri, H. Saxena, V. V. Agrawal, A. Gupta, M. K. Mukhopadhyay and S. K. Ghosh*; X-ray Reflectivity Study of the Interaction of an Imidazolium-Based Ionic Liquid with a Soft Supported Lipid Membrane, Langmuir (2017), 33, 1295-1304 (https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.6b03192)

15. R. P. Giri, M K. Mukhopadhyay, M. Mitra, A. Chakrabarti, M. K. Sanyal, S. K. Ghosh, S. Bera, L. B. Lurio, Y. Ma and S. K. Sinha; Differential adsorption of a membrane skeletal protein, spectrin, in phospholipid membranes; Euro Phys. Lett. (2017), 118, 58002 (http://iopscience.iop.org/article/10.1209/0295-5075/118/58002)

14. A. Barman, C. P. Saini, P. K. Sarkar, A. Roy, B. Satpati, D. Kanjilal, S. K. Ghosh, S. Dhar, and A. Kanjilal, Probing electron density across Ar+ irradiation-induced self-organized TiO2-xnanochannels for memory application, Applied Physics Letters (2016) 108, 244104 (https://aip.scitation.org/doi/full/10.1063/1.4954166)  

13. Y. Ma, S. K. Ghosh, D. A. DiLena, S. Bera, L. B. Lurio, A. N. Parikh, and S. K. Sinha, Cholesterol Partition and Condensing Effect in Phase-Separated Ternary Mixture Lipid Multilayers. Biophysical Journal (2016), 110, 1355-1366.

12. Y. Ma, S. K. Ghosh, S. Bera, Z. Jiang, C. M. Schleputz, E. Karapetrova, L. B. Lurio and S. K. Sinha Anomalous partitioning of water in coexisting liquid phases of lipid multilayers near 100% relative humidity. Phys.Chem.Chem.Phys., (2016), 18, 1225-1232

11. Y. Ma, S. K. Ghosh, S. Bera, Z. Jiang, S. Tristram-Nagle, L. B. Lurio and S. K. Sinha, Accurate calibration and control of relative humidity close to 100% by X-raying a DOPC multilayer. Phys. Chem. Chem. Phys. (2015), 17, 3570-3576.

10. S. K. Ghosh, B. Salgin, D. Pontoni, T. Reusch, P. Keil, D. Vogel, M. Rohwerder, H. Reichert, and T. Salditt, Structure and volta potential of lipid multilayers: Effect of x-ray irradiation, Langmuir (2013), 29, 815-824.

9. A. V. Radhakrishnan, S. K. Ghosh, G. Pabst, V. A. Raghunathan & A. K. Sood, Tuning DNA-amphiphile condensate architecture with strongly binding counterions Proc. Natl. Acad. Sci (PNAS), USA. (2012), 109, 6394-6398

8. S. K. Ghosh, S. Castorph, O. Konovalov, R. Jahn, T. Salditt, M. Holt, Measuring Ca2+ induced structural changes in lipid monolayers: implication for synaptic vesicles Exocytosis, Biophysical Journal, (2012), 102, 1394-1402

7. S. K. Ghosh, S. Aeffner and T. Salditt, Effect of PIP2 on DOPC bilayer structure and phase behavior: An x-ray scattering study ChemPhysChem, (2011), 12, 2633-2640

6. S. K. Ghosh, S. Castorph, O. Konovalov, R. Jahn, M. Holt and T. Salditt, In vitro study of interaction of synaptic vesicles with lipid membranes.; New J. Phys. (2010), 12, 105004

5. S. Castorph, L. Arleth, M. Sztucki, U. Vainio, S. K. Ghosh, R. Jahn, M. Holt and T. Salditt, Synaptic Vesicles Studied by SAXS: Derivation and Validation of a Model Form Factor J. Phys.: Conf. Ser. (2010), 247, 012015

4. S. K. Ghosh, V. Rathee, R. Krishnaswamy, V. A. Raghunathan & A. K. Sood, Re-entrant Phase Behaviour of a Concentrated Anionic Surfactant System with Strongly Binding Counterions,Langmuir (2009), 25, 8497-8506.

3. S. K. Ghosh & V. A. Raghunathan, Structure of Mesh Phases in a Cationic Surfactant System with Strongly Bound Counterions: Influence of the Surfactant head group and Counterions,Langmuir (2009), 25, 2622-2688

2. S. K. Ghosh, R. Ganpathy, R. Krishnaswamy, J. Bellare, V. A. Raghunathan & A. K. Sood, Structure of Mesh Phases in a Cationic Surfactant System with Strongly Bound Counterions.Langmuir (2007), 23, 3606-3614.

1. R. Krishnaswamy, S. K. Ghosh, S. Lakshmanan, V. A. Raghunathan & A. K. Sood, Phase Behaviour of a Concentrated Aqueous Solution of Cetyltrimethylammonium Bromide (CTAB) and Sodium Hydroxy Naphthoate (SHN), Langmuir (2005), 21, 10439-10443.

Journal Publications (submitted)

1. K. Bakshi, S. Mitra, V. K. Sharma, M. S. K. Jayadev, V. Garcia Sakai, R. Mukhopadhyay, A. Gupta and S. K. Ghosh, Mammalian cell death due to modulated structures and physical properties of cellular membrane induced by ionic liquids

Projects

  1. Title:Toxicity of Ionic liquids: Investigating with model cellular membrane
    Funding: UGC-DAE, Mumbai Centre
    Role: Principal Investigator (PI)
    Project Cost: 17 Lakhs (Approx.)
  2. Title: Biophysical study of forming and controlling nano-sized domain in model cellular membrane
    Funding: Scientific & Engineering Research Board (SERB), Gov. of India
    Role: Principal Investigator (PI)
    Project Cost: 35 Lakhs (Approx.)
  3. Title: Investigation of optical properties of Al2O3/ZrO2 nanocrystalline multilayers for ion beam dosimetry. Funding: Department of Atomic Energy (DAE), Board of Research in Nuclear Sciences (BRNS)
    Role: Co-Principal Investigator (Co-PI)
    Project Cost: 34.86 Lakhs.
  4. Title: Development of sensors for blast and blight diseases and stomatal activity measurement in rice (O. Sativa L.)                                                                                                                                                                                                                    Funding: National Agricultural Science Fund (NASF), ICAR                                                                                                                   Role: Co-Principal Investigator (Co-PI)                                                                                                                                                        Project Cost: ~68 Lakhs.